Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene

We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server. GAEV generates an easy-to-read table that summarizes the query gene name, the KO (KEGG Orthology) number, name of gene orthologs, functional definition of the ortholog, and the functional pathways that query gene has been mapped to. Via links to KEGG pathway maps, users can directly examine the interaction between gene products involved in the same molecular pathway. We provide a usage example by annotating the newly published freshwater microcrustacean genome. This gene-centered view of gene function and Daphnia pulex pathways will greatly facilitate the genome annotation of non-model species and metagenomics data. GAEV runs on a Windows or Linux system equipped with Python 3 and provides easy accessibility to users with no prior Unix command line experience. Sen Xu ( ) Corresponding author: [email protected] : Investigation, Methodology, Software, Writing – Original Draft Preparation, Writing – Review & Editing; : Author roles: Huynh T Xu S Conceptualization, Supervision, Writing – Original Draft Preparation, Writing – Review & Editing No competing interests were disclosed. Competing interests: Huynh T and Xu S. How to cite this article: Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene Function Annotations and 2018, :416 (doi: Associated Molecular Pathways [version 1; referees: awaiting peer review] F1000Research 7 ) 10.12688/f1000research.14012.1 © 2018 Huynh T and Xu S. This is an open access article distributed under the terms of the , Copyright: Creative Commons Attribution Licence which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. University of Texas at Arlington Grant information: The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 29 Mar 2018, :416 (doi: ) First published: 7 10.12688/f1000research.14012.1 Referee Status: AWAITING PEER REVIEW 29 Mar 2018, :416 (doi: ) First published: 7 10.12688/f1000research.14012.1 29 Mar 2018, :416 (doi: ) Latest published: 7 10.12688/f1000research.14012.1 v1 Page 1 of 6 F1000Research 2018, 7:416 Last updated: 30 MAR 2018